The worst mistake you can make when doing ozone therapy
Paola Dziwetzki | May 14, 2022 |

The worst mistake when doing ozone treatments is to combine them with glutathione IVs.
People who receive glutathione intravenously often end up with crushing depression, become suicidal, or have panic attacks. They report “feeling like dying”, loss of hearing, debilitating tingling and burning sensations all over the body, electric shocks, or crushing back pain. Those symptoms sometimes pass after a few weeks, some last for a year or longer. Some have reported losing the ability to walk.
Given that glutathione is a natural molecule which is present in each of our cells, people have a hard time believing that it could cause such horrendous side effects.
Doctors and naturopaths alike are completely oblivious to its dangers, and often ignoring or gaslighting patients who were hurt.
But the reports are undeniable. People from all around the globe report the same peculiar symptoms.
So what's going on and what role does ozone therapy play in this?
Have I ever taken glutathione? I have never received glutathione in any shape or form.
Consequently, this article is NOT based on my personal experience.
It is based on countless conversations I had with people who felt they were badly damaged by oral or intravenous glutathione administrations and who were disbelieved, ignored, or maligned by the very people who hurt them.
The astounding thing I encountered was that people from different continents and countries, who had never met each other often described the exact same things with the exact same words: “feeling like dying” or having “two rods in my skull”.
It is also important to understand that I have talked probably to just as many people who swear that glutathione was the best thing that ever happened to them and they don’t ever want to stop taking it.
There were also those who went from loving glutathione to being badly damaged by it with the next dose. And that after months or years without experiencing any negative side effects.
To this day I don’t have a final explanation why those adverse reactions occur, but there are several possible theories, see further below.
What is glutathione?
Glutathione (GSH) is a sulfur based molecule which is naturally produced by the human body. It is one of the most potent antioxidants. It protects our cells from free radicals and oxidative stress. [2]
In addition it also [1] [3]:
Our bodies would not be able to function without it.
And yet, when given in large dosages, especially intravenously, it often creates horrific adverse reactions in some people.
Glutathione can be taken orally, vaporized and inhaled or administered intravenously (either as a drip or as a push).
Although people have reported adverse events after all types of glutathione administrations, the IVs seem to be the most dangerous.
What is the connection between glutathione and ozone therapy?
The connection between glutathione and ozone therapy is that many ozone therapists administer glutathione together with ozone, for a variety of reasons.
The justifications range from wanting to prevent an ozone induced Herxheimer reaction, to prevent an ozone overdose, or simply because of the assumed health benefits of glutathione.
Sometimes glutathione is added to the ozone administration without the patient’s knowledge. The observed adverse effects are then explained away as a die-off reaction from ozone. Or they are simply ignored and the patient is misbelieved.
Does ozone therapy make glutathione more dangerous?
There is no reason to believe that ozone therapy has any impact on whether an individual will experience a good or bad reaction after glutathione.
There are many members of various toxic metal detox groups (since GSH is preferably given to help with assumed chronic mercury and other metal poisonings) who have never received ozone treatments in their lives but who report the most daunting adverse reactions after a GSH administration.
What are the possible explanations for the adverse effects after GSH?
The issue is mostly ignored by the medical community, as far as I know. There are no public forums dedicated to glutathione adverse effects, nor have any studies been conducted on the topic, nor is there any individual who has committed their work to this subject.
Consequently, the problem remains mostly unexamined.
Here are some theories which have been proposed:
1. Cholestasis
This is a theory I am proposing: glutathione causes backed-up bile (cholestasis) in the liver. Some of the bile then flows back into the blood and poisons the patient. This causes all sorts of dramatic symptoms.
Why would this happen? If bile ducts are inflamed, narrowed, scarred, leaky, or missing, bile cannot be properly transported from the liver into the small intestine, as it should in a healthy human being.
In such a case the bile remains in the liver and causes cirrhosis. Some of the bile salts enter the blood and do damage in a variety of organs.
Glutathione, being a potent liver tonic, probably promotes bile flow. If too much gluathione is administered via IV, a lot of bile is produced which then encounters the blocked bile ducts.
If this is what causes the negative responses to gluathione IVs, then a protocol that helps open bile ducts and that helps to detox the liver should help.
This could be achieved with lactoferrin (low dose starting at 15 to 30 mg, according to Dr. Garrett Smith), low vitamin A diet, soluble fiber (beans, psyllium), activated charcoal, zinc, magnesium, low dose Alpha Lipoic Acid, heat packs, infrared light, or saunas.
2. Mercury toxicity
Some assume that the adverse reactions could be due to mobilization and misplacement of mercury (or other toxic metals) in people who suffer from chronic metal poisoning, for example from amalgams.
Anecdotal reports seem to suggest that patients who still have their amalgam fillings are at a higher risk of developing a negative reaction.
Especially the late Andrew Cutler, a self-taught mercury-detox expert, ascribed to this idea. He said that glutathione, being a single thiol agent, was not able to form bonds strong enough to escort mercury out of the body. Instead, only weak bonds were created. This resulted in mercury being moved around into sensitive tissue and causing oxidative damage.
What does not quite add up with this explanation, is the fact that adverse reactions are also experienced by people who never had amalgam fillings in their life nor were ever exposed to toxic metals to any significant degree.
3. Thiamine (B1) deficiency
Vitamin B1 deficiency is possibly one of the most widespread nutrient deficiencies in the developed world, but also one of the most unrecognized ones, according to some researchers.
Many of the symptoms experienced by glutathione damaged patients perfectly match those of thiamine deficiency [4] [5] [6].
But how could large dosages of glutathione trigger thiamine deficiency?
Maybe it doesn't trigger it, but brings an existing GSH deficiency to the front. In the same way high dosages of thiamine can create functional magnesium, B9, B2, and B12 deficiencies. [8]
So, it is possibly a form of “Refeeding Syndrome”. [7]
4. Riboflavin (B2) and selenium deficiencies
Glutathione is constantly being recycled from the reduced to the oxidized form and back again.
In order to accomplish this, vitamin B2 (riboflavin) and selenium are needed. If there is a deficiency in those nutrients, could it be that mega injections of glutathione could lead to a breakdown of this system with the resulting crashes?
Something similar happens when B1 deficient patients are given B1 in large dosages – it has a cascading effect where B2, B9, and B12 deficiencies can be exacerbated or created.
People who receive glutathione intravenously often end up with crushing depression, become suicidal, or have panic attacks. They report “feeling like dying”, loss of hearing, debilitating tingling and burning sensations all over the body, electric shocks, or crushing back pain. Those symptoms sometimes pass after a few weeks, some last for a year or longer. Some have reported losing the ability to walk.
Given that glutathione is a natural molecule which is present in each of our cells, people have a hard time believing that it could cause such horrendous side effects.
Doctors and naturopaths alike are completely oblivious to its dangers, and often ignoring or gaslighting patients who were hurt.
But the reports are undeniable. People from all around the globe report the same peculiar symptoms.
So what's going on and what role does ozone therapy play in this?
Have I ever taken glutathione? I have never received glutathione in any shape or form.
Consequently, this article is NOT based on my personal experience.
It is based on countless conversations I had with people who felt they were badly damaged by oral or intravenous glutathione administrations and who were disbelieved, ignored, or maligned by the very people who hurt them.
The astounding thing I encountered was that people from different continents and countries, who had never met each other often described the exact same things with the exact same words: “feeling like dying” or having “two rods in my skull”.
It is also important to understand that I have talked probably to just as many people who swear that glutathione was the best thing that ever happened to them and they don’t ever want to stop taking it.
There were also those who went from loving glutathione to being badly damaged by it with the next dose. And that after months or years without experiencing any negative side effects.
To this day I don’t have a final explanation why those adverse reactions occur, but there are several possible theories, see further below.
What is glutathione?
Glutathione (GSH) is a sulfur based molecule which is naturally produced by the human body. It is one of the most potent antioxidants. It protects our cells from free radicals and oxidative stress. [2]
In addition it also [1] [3]:
- is vital for the proper functioning of certain enzymes
- participates in the production and repair of DNA
- helps in the metabolism of drugs
- is involved in the production of proteins in the human body
Our bodies would not be able to function without it.
And yet, when given in large dosages, especially intravenously, it often creates horrific adverse reactions in some people.
Glutathione can be taken orally, vaporized and inhaled or administered intravenously (either as a drip or as a push).
Although people have reported adverse events after all types of glutathione administrations, the IVs seem to be the most dangerous.
What is the connection between glutathione and ozone therapy?
The connection between glutathione and ozone therapy is that many ozone therapists administer glutathione together with ozone, for a variety of reasons.
The justifications range from wanting to prevent an ozone induced Herxheimer reaction, to prevent an ozone overdose, or simply because of the assumed health benefits of glutathione.
Sometimes glutathione is added to the ozone administration without the patient’s knowledge. The observed adverse effects are then explained away as a die-off reaction from ozone. Or they are simply ignored and the patient is misbelieved.
Does ozone therapy make glutathione more dangerous?
There is no reason to believe that ozone therapy has any impact on whether an individual will experience a good or bad reaction after glutathione.
There are many members of various toxic metal detox groups (since GSH is preferably given to help with assumed chronic mercury and other metal poisonings) who have never received ozone treatments in their lives but who report the most daunting adverse reactions after a GSH administration.
What are the possible explanations for the adverse effects after GSH?
The issue is mostly ignored by the medical community, as far as I know. There are no public forums dedicated to glutathione adverse effects, nor have any studies been conducted on the topic, nor is there any individual who has committed their work to this subject.
Consequently, the problem remains mostly unexamined.
Here are some theories which have been proposed:
1. Cholestasis
This is a theory I am proposing: glutathione causes backed-up bile (cholestasis) in the liver. Some of the bile then flows back into the blood and poisons the patient. This causes all sorts of dramatic symptoms.
Why would this happen? If bile ducts are inflamed, narrowed, scarred, leaky, or missing, bile cannot be properly transported from the liver into the small intestine, as it should in a healthy human being.
In such a case the bile remains in the liver and causes cirrhosis. Some of the bile salts enter the blood and do damage in a variety of organs.
Glutathione, being a potent liver tonic, probably promotes bile flow. If too much gluathione is administered via IV, a lot of bile is produced which then encounters the blocked bile ducts.
If this is what causes the negative responses to gluathione IVs, then a protocol that helps open bile ducts and that helps to detox the liver should help.
This could be achieved with lactoferrin (low dose starting at 15 to 30 mg, according to Dr. Garrett Smith), low vitamin A diet, soluble fiber (beans, psyllium), activated charcoal, zinc, magnesium, low dose Alpha Lipoic Acid, heat packs, infrared light, or saunas.
2. Mercury toxicity
Some assume that the adverse reactions could be due to mobilization and misplacement of mercury (or other toxic metals) in people who suffer from chronic metal poisoning, for example from amalgams.
Anecdotal reports seem to suggest that patients who still have their amalgam fillings are at a higher risk of developing a negative reaction.
Especially the late Andrew Cutler, a self-taught mercury-detox expert, ascribed to this idea. He said that glutathione, being a single thiol agent, was not able to form bonds strong enough to escort mercury out of the body. Instead, only weak bonds were created. This resulted in mercury being moved around into sensitive tissue and causing oxidative damage.
What does not quite add up with this explanation, is the fact that adverse reactions are also experienced by people who never had amalgam fillings in their life nor were ever exposed to toxic metals to any significant degree.
3. Thiamine (B1) deficiency
Vitamin B1 deficiency is possibly one of the most widespread nutrient deficiencies in the developed world, but also one of the most unrecognized ones, according to some researchers.
Many of the symptoms experienced by glutathione damaged patients perfectly match those of thiamine deficiency [4] [5] [6].
But how could large dosages of glutathione trigger thiamine deficiency?
Maybe it doesn't trigger it, but brings an existing GSH deficiency to the front. In the same way high dosages of thiamine can create functional magnesium, B9, B2, and B12 deficiencies. [8]
So, it is possibly a form of “Refeeding Syndrome”. [7]
4. Riboflavin (B2) and selenium deficiencies
Glutathione is constantly being recycled from the reduced to the oxidized form and back again.
In order to accomplish this, vitamin B2 (riboflavin) and selenium are needed. If there is a deficiency in those nutrients, could it be that mega injections of glutathione could lead to a breakdown of this system with the resulting crashes?
Something similar happens when B1 deficient patients are given B1 in large dosages – it has a cascading effect where B2, B9, and B12 deficiencies can be exacerbated or created.
Vitamin B1 needs B2 as a co-factor. So, if B2 has been used up by the glutathione cycle, this could possibly bring about a functional B1 deficiency, see above.
If that's the case, then supplying the patient with B1, B2, selenium, and possibly other cofactors (magnesium, molybdenum, B12, B9, iodine) could potentially fix the adverse reactions.
5. Genetic predispositions
Some theorize that certain genetic expressions (which are often wrongly called “mutations”) are responsible for not being able to deal with glutathione in large dosages. The main culprit is believed to be the CBS, the MTHFR, or some other allele.
Personally, I am not convinced that this is the case, since there are a number of people who have those genetic setups but are benefiting from glutathione IVs.
6. Oxalate displacement
Many oxalate experts are convinced that those plant toxins deplete glutathione [9] [10]. Oxalates are tiny crystals contained in high concentrations in certain plant foods. Is it possible that an intravenous administration of glutathione leads to a massive movement of those sharp objects, wrecking havoc as a result?
7. Other mineral deficiencies
Molybdenum could be one of those, see the comment section below. There, a reader reports that her practitioner reversed a negative reaction to glutathione by quickly giving her molybdenum.
Complete article with "Real life testimonials after glutathione administration" can be accessed via weblink, https://thepowerofozone.com/worst-mistake-can-make-ozone-therapy/.
If that's the case, then supplying the patient with B1, B2, selenium, and possibly other cofactors (magnesium, molybdenum, B12, B9, iodine) could potentially fix the adverse reactions.
5. Genetic predispositions
Some theorize that certain genetic expressions (which are often wrongly called “mutations”) are responsible for not being able to deal with glutathione in large dosages. The main culprit is believed to be the CBS, the MTHFR, or some other allele.
Personally, I am not convinced that this is the case, since there are a number of people who have those genetic setups but are benefiting from glutathione IVs.
6. Oxalate displacement
Many oxalate experts are convinced that those plant toxins deplete glutathione [9] [10]. Oxalates are tiny crystals contained in high concentrations in certain plant foods. Is it possible that an intravenous administration of glutathione leads to a massive movement of those sharp objects, wrecking havoc as a result?
7. Other mineral deficiencies
Molybdenum could be one of those, see the comment section below. There, a reader reports that her practitioner reversed a negative reaction to glutathione by quickly giving her molybdenum.
Complete article with "Real life testimonials after glutathione administration" can be accessed via weblink, https://thepowerofozone.com/worst-mistake-can-make-ozone-therapy/.